E.C.G. Interatrial Block Predicts Stroke, Atrial Fibrillation. 10/10/25

10/10/2025 Episodio 101
E.C.G. Interatrial Block Predicts Stroke, Atrial Fibrillation. 10/10/25

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Episode Synopsis

Welcome to Cardiology Today – Recorded October 10, 2025. This episode summarizes 5 key cardiology studies on topics like sedentary behavior and electrocardiogram. Key takeaway: E.C.G. Interatrial Block Predicts Stroke, Atrial Fibrillation..
Article Links:
Article 1: Lung transplantation for chronic thromboembolic pulmonary hypertension – a case series. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
Article 2: Long-term prognosis of pure and impure tachycardiomyopathy. (ESC heart failure)
Article 3: Physical Activity, Gut Microbiota, and the Risk of Dyslipidemia in a Community-Based Cohort Study. (Journal of the American Heart Association)
Article 4: Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair: A Target Trial Emulation. (Journal of the American Heart Association)
Article 5: Interatrial Block Detected by a Series of ECGs Before and During Acute Coronary Syndrome Predicts Atrial Fibrillation, Atrial Flutter, and Ischemic Stroke. (Journal of the American Heart Association)
Full episode page: https://podcast.explainheart.com/podcast/e-c-g-interatrial-block-predicts-stroke-atrial-fibrillation-10-10-25/
Featured Articles
Article 1: Lung transplantation for chronic thromboembolic pulmonary hypertension – a case series.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41067464
Summary: This case series describes the outcomes of six patients with chronic thromboembolic pulmonary hypertension who underwent lung transplantation. These patients either had inoperable disease or residual pulmonary hypertension after pulmonary endarterectomy, leading to end-stage right heart failure. The findings indicate that lung transplantation serves as a life-saving therapeutic option for patients with severe chronic thromboembolic pulmonary hypertension who are not candidates for or have failed other interventions. This highlights its critical role in managing refractory cases.
Article 2: Long-term prognosis of pure and impure tachycardiomyopathy.
Journal: ESC heart failure
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41065522
Summary: This prospective, monocentric, observational study recruited 456 patients with de novo, acute decompensated heart failure with reduced ejection fraction, classifying them into pure tachycardia-induced cardiomyopathy, impure tachycardia-induced cardiomyopathy, and other heart failure etiologies. The study aimed to clarify the long-term prognosis of both pure and impure tachycardia-induced cardiomyopathy. While the study design is established for comparing these prognoses, specific findings regarding the long-term outcomes are not detailed in the provided abstract.
Article 3: Physical Activity, Gut Microbiota, and the Risk of Dyslipidemia in a Community-Based Cohort Study.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41065289
Summary: This prospective community-based cohort study involved 2,942 Chinese adults, assessing the joint association between moderate-to-vigorous physical activity and sedentary time on dyslipidemia risk using self-reported questionnaires. A subcohort of 754 participants also had their one-year gut microbial changes associated with moderate-to-vigorous physical activity assessed. The study aims to clarify whether moderate-to-vigorous physical activity mitigates the detrimental effects of sedentary behavior on dyslipidemia and to elucidate the link between physical activity and gut microbiota. Specific findings regarding these associations are not detailed in the provided abstract.
Article 4: Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair: A Target Trial Emulation.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41065286
Summary: This study employed a target trial emulation methodology to compare the efficacy and safety of single versus dual antiplatelet therapy after standard endovascular aneurysm repair. The investigation focused on patients undergoing endovascular aneurysm repair for abdominal aortic aneurysms who did not have established atherosclerotic cardiovascular disease, where optimal antiplatelet regimens are currently uncertain. The primary objective was to determine the superior antiplatelet strategy for this specific patient population. Specific findings regarding comparative efficacy and safety are not detailed in the provided abstract.
Article 5: Interatrial Block Detected by a Series of ECGs Before and During Acute Coronary Syndrome Predicts Atrial Fibrillation, Atrial Flutter, and Ischemic Stroke.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41065269
Summary: This retrospective study analyzed 206,668 standard electrocardiograms from 9,674 consecutive patients diagnosed with acute coronary syndrome between 2007 and 2018. The research found that interatrial block, detected through a series of electrocardiograms taken before and during acute coronary syndrome, significantly predicts future occurrences of atrial fibrillation, atrial flutter, and ischemic stroke. This finding highlights interatrial block as a critical, easily identifiable risk marker for subsequent cerebrovascular and atrial arrhythmogenic events in this patient cohort, emphasizing the value of diligent electrocardiogram monitoring.
Transcript

Today’s date is October 10, 2025. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Lung transplantation for chronic thromboembolic pulmonary hypertension – a case series. This case series describes the outcomes of six patients with chronic thromboembolic pulmonary hypertension who underwent lung transplantation. These patients either had inoperable disease or residual pulmonary hypertension after pulmonary endarterectomy, leading to end-stage right heart failure. The findings indicate that lung transplantation serves as a life-saving therapeutic option for patients with severe chronic thromboembolic pulmonary hypertension who are not candidates for or have failed other interventions. This highlights its critical role in managing refractory cases.
Article number two. Long-term prognosis of pure and impure tachycardiomyopathy. This prospective, monocentric, observational study recruited 456 patients with de novo, acute decompensated heart failure with reduced ejection fraction, classifying them into pure tachycardia-induced cardiomyopathy, impure tachycardia-induced cardiomyopathy, and other heart failure etiologies. The study aimed to clarify the long-term prognosis of both pure and impure tachycardia-induced cardiomyopathy. While the study design is established for comparing these prognoses, specific findings regarding the long-term outcomes are not detailed in the provided abstract.
Article number three. Physical Activity, Gut Microbiota, and the Risk of Dyslipidemia in a Community-Based Cohort Study. This prospective community-based cohort study involved 2,942 Chinese adults, assessing the joint association between moderate-to-vigorous physical activity and sedentary time on dyslipidemia risk using self-reported questionnaires. A subcohort of 754 participants also had their one-year gut microbial changes associated with moderate-to-vigorous physical activity assessed. The study aims to clarify whether moderate-to-vigorous physical activity mitigates the detrimental effects of sedentary behavior on dyslipidemia and to elucidate the link between physical activity and gut microbiota. Specific findings regarding these associations are not detailed in the provided abstract.
Article number four. Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair: A Target Trial Emulation. This study employed a target trial emulation methodology to compare the efficacy and safety of single versus dual antiplatelet therapy after standard endovascular aneurysm repair. The investigation focused on patients undergoing endovascular aneurysm repair for abdominal aortic aneurysms who did not have established atherosclerotic cardiovascular disease, where optimal antiplatelet regimens are currently uncertain. The primary objective was to determine the superior antiplatelet strategy for this specific patient population. Specific findings regarding comparative efficacy and safety are not detailed in the provided abstract.
Article number five. Interatrial Block Detected by a Series of ECGs Before and During Acute Coronary Syndrome Predicts Atrial Fibrillation, Atrial Flutter, and Ischemic Stroke. This retrospective study analyzed 206,668 standard electrocardiograms from 9,674 consecutive patients diagnosed with acute coronary syndrome between 2007 and 2018. The research found that interatrial block, detected through a series of electrocardiograms taken before and during acute coronary syndrome, significantly predicts future occurrences of atrial fibrillation, atrial flutter, and ischemic stroke. This finding highlights interatrial block as a critical, easily identifiable risk marker for subsequent cerebrovascular and atrial arrhythmogenic events in this patient cohort, emphasizing the value of diligent electrocardiogram monitoring.
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Keywords
sedentary behavior, electrocardiogram, tachycardia-induced cardiomyopathy, abdominal aortic aneurysm, lung transplantation, decompensated heart failure, heart failure with reduced ejection fraction, metabolic health, endovascular aortic repair, long-term prognosis, pulmonary endarterectomy, atherosclerotic cardiovascular disease, acute coronary syndrome, antiplatelet therapy, atrial fibrillation, ischemic stroke, physical activity, dual antiplatelet therapy, chronic thromboembolic pulmonary hypertension, dyslipidemia, interatrial block, gut microbiota, pulmonary vascular disease, right heart failure.
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Concise summaries of cardiovascular research for professionals.
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