Send us a text🧠 Clinical Myth:“Delay levodopa to delay motor complications.”🧪 LEAP Trial (Levodopa in Early Parkinson’s):Compared early start vs 40-week delayed start.5-year follow-up showed no difference in motor fluctuations or dyskinesia.📈 Key Outcomes:Early levodopa = better function earlier, no long-term harm.Wearing off effect was similar in both groups.🧩 Clinical Takeaway:Don’t hold back levodopa if patient is symptomatic.Starting early improves quality of life without hastening decline.Personalize the approach — don’t delay just for dogma.

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