Paraneoplastic Syndromes: Insights From AAN 2025

10/06/2025

Listen "Paraneoplastic Syndromes: Insights From AAN 2025"

Episode Synopsis

In this episode of Better Edge, Northwestern Medicine Neurologist Shailee Shah, MD, and Neuro-oncologist Ditte Primdahl, MD, unpack the latest advancements in paraneoplastic syndrome management, highlighted at the 2025 American Academy of Neurology Annual Meeting.  
Together, they explore:

The complex interplay between immune checkpoint inhibitors and autoimmune neurologic syndromes
Emerging therapies, including CD19-directed CAR T-cell treatments
Updates to diagnostic criteria and risk stratification using high-risk autoantibodies
The role of predictive biomarkers and advanced omics in diagnosis
The launch of a dedicated paraneoplastic clinic at Northwestern Medicine

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