Ep. 219 New Frontiers in Pediatric Hearing Loss: Implants, Gene Therapy, and CMV with Dr. Daniela Carvalho

22/04/2025 45 min
Ep. 219 New Frontiers in Pediatric Hearing Loss: Implants, Gene Therapy, and CMV with Dr. Daniela Carvalho

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Episode Synopsis

Are new solutions for pediatric hearing loss finally within earshot? In this episode of the Back Table ENT Podcast, we talk with Dr. Daniela Carvalho, pediatric otolaryngologist and director of the Cochlear Implant Program at Rady Children's Hospital in San Diego.

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SYNPOSIS

Dr. Carvalho discusses the latest advancements and practices in the field of pediatric hearing loss, including newer indications for cochlear implants and innovative gene therapies. They delve into the genetic causes of congenital hearing loss, current screening practices, and various gene therapies being tested for hearing deficiencies, such as those involving the OTOF gene and its application through viral vectors. The conversation also touches on the potential for future treatments, including completely implantable cochlear devices and the role of vaccines in preventing CMV-related hearing loss.

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TIMESTAMPS

00:00 - Introduction
01:54 - Understanding Congenital Hearing Loss and Screening
05:41 - Challenges with Older Children and Hearing Loss
08:48 - Cochlear Implants: Indications and Advances
15:59 - Exploring Gene Therapy for Hearing Loss
23:54 - Challenges and Considerations in Gene Therapy
25:23 - Counseling Families on Hearing Loss
27:04 - Future of Genetic Therapy and Cochlear Implants
32:46 - Addressing Congenital CMV
40:59 - Final Thoughts and Future Research

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RESOURCES

Dr. Daniela Carvalho
https://www.rchsd.org/doctors/daniela-carvalho-md-mmm/

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