We sit down with Prof. Bart van de Sluis, Professor of Molecular Genetics and Translational Biology at the University of Groningen (UMCG). His research unravels the molecular mechanisms that control lipid metabolism and endo-lysosomal cholesterol transport, key processes in cardiometabolic diseases such as fatty liver disease and atherosclerosis. Prof. van de Sluis leads a research group dedicated to understanding how receptor trafficking and inflammation are regulated, with a focus on the NF-κB signaling pathway. Using advanced cellular and mouse models, including CRISPR/Cas approaches, his team pushes the boundaries of molecular medicine. Beyond his research, he heads the Transgenic Mouse Clinic for Aging Research (CRISPR facility). Join us as we talk about his scientific journey, the challenges of translational research, and his vision for the future of molecular biology and cardiovascular science.-------------------------------------------------Script-prep: Hana Bartuskova, Maria Giovanna Lupo, Sanne Maas, Tatyana StorozhenkoInterviewer: Sanne Maas

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