In our fifth episode of Afaxys Candid Conversations in Public Health, we discuss the recently published “StepUp” randomized controlled trial of male partner treatment for the prevention of bacterial vaginosis (BV) recurrence in female partners with our expert guests, Dr. Craig Cohen and Dr. Ina Park. Building on our previous episode 4, part 2, we take a deep dive into the American College of Obstetricians and Gynecologists Clinical Practice Update: Concurrent Sexual Partner Therapy to Prevent Bacterial Vaginosis Recurrence. This guidance was based on the StepUp clinical trial and published after we spoke with Dr. Christina Muzny in our last episode.Today’s discussion covers why the vaginal microbiome is central to BV, what the recent clinical trial from Australia actually showed, a critical look at the new clinical practice update, and why applying the Australian trial findings in U.S. clinics requires appreciation of the nuances of the trial population. Our experts also explore whether BV should be viewed as a sexually transmitted infection, plus the practical challenges of treating male partners. They also highlight emerging strategies—such as microbiome-restoring therapies—and key questions that still need research before widespread adoption.Disclosures:Dr. Cohen discloses that he is on the scientific committee for Osel and Evvy.Dr. Park has no disclosures.Resources:***Free CME!*** STI Expert Hour Webinar - Male Partner Treatment to Prevent BV Recurrence: Evidence and Implementation on December 18, 2025Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis Bacterial Vaginosis — Time to Treat Male Partners Getting Everyone on Board to Break the Cycle of Bacterial Vaginosis (BV) Recurrence: A Qualitative Study of Partner Treatment for BVACOG PUBLICATIONS: CLINICAL PRACTICE UPDATEConcurrent Sexual Partner Therapy to Prevent Bacterial Vaginosis RecurrenceMelbourne Sexual Health Centre - BV in focusEducational content only — not a substitute for professional medical advice. Opinions are those of the speakers and not necessarily of Afaxys. Visit Afaxys.com for resources.

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