Is there a "perfect" timing for a procedure, treatment or advanced medical intervention when one is suffering from illness and disease?  There are several identifiable factors/elements to consider yet the the guidelines for clinicians are only a collective guide but not a prescriptive "rule" when the life of a human being is concerned.  The delicate balance of risk versus harm, and benefit vs harm must be addressed by the physician who is also aware of the real-world evidence and the guidelines or protocols of Medicine.

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