Can USC upset Notre Dame? The Trojans face tough odds as nearly double-digit underdogs against the Fighting Irish. After a dominant win over Michigan, USC heads to South Bend, but struggles on the road and a powerful Notre Dame defense could spell trouble. With injuries plaguing the backfield, can USC's offense rise to the occasion, protect their QB, and contain Notre Dame's explosive run game to pull off a massive rivalry week upset?The Daily News Now! - Every city. Every story. AI Powered. Hosted on Acast. See acast.com/privacy for more information.

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