In this frank discussion on Up One, host Sawyer Stone is joined by Dr. Bill Andrews and longevity physician Dr. Sandra Kaufmann to demystify menopause, an event Dr. Kaufmann calls "a canary in the coal mine" for a woman's aging process. They debate the underlying cause, with Dr. Andrews questioning if it's a random genetic accident linked to 'Mitochondria Eve' or a mysterious, non-linear timing mechanism. Dr. Kaufmann offers the view that it's fundamentally ovarian failure driven by high metabolic demands , and they address common symptoms like osteoporosis, fatigue, and the surprising link between estrogen decline and LDL cholesterol. They also discuss the crucial timing of hormone replacement therapy and the non-linear "cobweb" of interconnected molecular pathways that influence a woman's transition.References:Osteo Strong: https://www.osteostrong.me/The Kaufmann Protocolhttps://kaufmannprotocol.com/Follow Dr. Kaufmann on Instagram https://www.instagram.com/kaufmannlongevity/?hl=enSend Dr. Bill an email! [email protected]

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