Stories on lung organoids and autism were some of the most read this week. We kicked things off by digging into recent breakthroughs in both areas including an automated method for manufacturing iPSC-derived lung organoids and how a combination of supplements reduced autism-linked behaviors in mice. Still on the topic of new research, we discussed how a protein in the extracellular matrix helps muscle stem cells repair aging muscles. In business news, the bidding war between Lundbeck and Alkermes over Avadel Pharmaceuticals has ended. We talk about the possible implications of Lundbeck’s decision to back out and next steps for Alkermes. Then we dive into Protego Biopharma’s recent fundraising round, and efforts to develop small-molecule pharmacological chaperones that modulate protein stability in disease.   Join GEN editors Corinna Singleman, PhD, Alex Philippidis, and Uduak Thomas for a discussion of the latest biotech and biopharma news.  Listed below are links to the GEN stories referenced in this episode of Touching Base:  Lung Organoids Generated in Bulk Using Stirred Bioreactor Technology GEN, December 1, 2025Autism-Linked Behaviors in Mice Reduced by Nutrient TrioGEN, December 3, 2025Muscle Stem Cells Bolstered by ECM Protein Tenascin-CGEN, December 5, 2025 Protego Closes $130M Series B to Fund Pivotal Trial of AL Amyloidosis CandidateBy Alex Philippidis, GEN Edge, December 3, 2025Lundbeck Ends Bidding War for Avadel, After Alkermes’ Up-to-$2.37B OfferBy Alex Philippidis, GEN Edge, December 1, 2025Touching Base Podcast Hosted by Corinna Singleman, PhD  Behind the Breakthroughs Hosted by Jonathan D. Grinstein, PhD  Hosted on Acast. See acast.com/privacy for more information.

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