Dr. Matt Kaeberlein is one of the world’s most respected scientists in the field of aging biology. In this episode, we unpack the real science of longevity — from mTOR inhibition and rapamycin to calorie restriction, biomarkers of aging, and what most people get wrong about lifespan vs healthspan.

We go beyond the hype to ask: What actually works? What’s still theoretical? And where is the frontier of human aging research heading?

Topics we cover:

The biology of aging: mTOR, autophagy, senescence

Rapamycin in humans: What we know and don’t

Why extending healthspan matters more than living longer

Matt’s views on supplements, diet, and biomarkers

The most misunderstood concepts in anti-aging

Referenced studies include:

Dog Aging Project

Interventions Testing Program

Rapamycin human trial data
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I’m Louisa Nicola — clinical neuophysiologist — Alzheimer’s prevention specialist — founder of Neuro Athletics.

My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention.
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