A best of episode where Russ interviews one of his bioengineering colleagues,  Fan Yang, about some of the fascinating work she’s doing in the realm of tissue engineering. Hear more about the ways her lab is modeling human tissue to help develop a better understanding of how we might effectively replace damaged tissues and alleviate a number of health concerns.Episode Reference Links:Fan Yang's Stanford Profile: WebsiteFan Yang’s Stanford Lab: WebsiteEp.174 Regenerating and Rejuvenating Human Tissues: Website / YouTube (original episode)Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionHost Russ Altman introduces guest Fan Yang, a bioengineer at Stanford.(00:03:15) The Basics of Tissue EngineeringThe purpose and significance of tissue engineering, emphasizing its role in addressing critical medical needs like late-stage arthritis.(00:04:23) Challenges in Tissue EngineeringTechnical hurdles in creating viable tissues for clinical use, such as integrating these tissues into the human body.(00:07:00) 3D Printing and In Situ PolymerizationTechnological advances in shaping tissues using 3D printing and the benefits of in situ polymerization to adapt to complex tissue shapes.(00:09:15) Specific Challenges with CartilageThe challenges specific to cartilage regeneration, explaining why it has been a difficult tissue to replicate and heal.(00:13:56) Micro Ribbon Based HydrogelsExplanation of micro ribbon based hydrogels, a new development aimed at improving tissue regeneration.(00:19:16) Cancer Research and Tissue EngineeringHow tissue engineering technologies are not only pivotal for therapeutic uses but also crucial for understanding diseases and aiding drug discovery.(00:24:38) Regulatory Challenges and CommercializationThe regulatory and commercialization challenges facing new medical technologies, including the need for industry partnerships and the role of the FDA(00:26:20) Conclusion
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