A Risk Stratification Model for Low Stage Uterine leiomyosarcoma

07/07/2022 17 min
A Risk Stratification Model for Low Stage Uterine leiomyosarcoma

Listen "A Risk Stratification Model for Low Stage Uterine leiomyosarcoma"

Episode Synopsis

Uterine leiomyosarcoma is the most common uterine mesenchymal malignancy. The majority present at stage I with variable clinical outcome.

In this episode of ModPath Chat, Dr. David Chapel discusses his recently published multi-institutional study proposing a novel risk stratification model (shown below) for low stage uterine leiomyosarcoma.

Risk score = (coagulative necrosis)(1) + (mitoses > 25 per 2.4mm2)(2) + (atypical mitoses)(2) + (lymphovascular invasion)(3) + (serosal abutment)(5)