Disclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, learn how sun damage, known as ultraviolet radiation (“UVR”), significantly influences the composition of the skin microbiome and is known to modulate the immune system, potentially leading to immunosuppression. Tune in to learn how this UV-induced immune suppression is correlated with seasonal increases in herpes zoster (shingles) cases. Link to Source(s):American Journal of Epidemiology (2021): Association of Sunburn With Increased Risk of Herpes Zoster:https://academic.oup.com/aje/article/190/9/1814/6175319#354359554Frontiers in Microbiology (2024): The Microbial Imprint on Skin Barrier Integrity and Inflammation:https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1427770/fullPubMed (2003): Ultraviolet radiation activates lytic cycle of Epstein-Barr virus:https://pubmed.ncbi.nlm.nih.gov/12558343/PubMed (2016): UV radiation induces viral reactivation in herpesviruses:https://pubmed.ncbi.nlm.nih.gov/26963841/PubMed (2016): The skin microbiome in immunocompromised patients:https://pubmed.ncbi.nlm.nih.gov/27559331/PubMed (2018): The role of the skin microbiome in atopic dermatitis:https://pubmed.ncbi.nlm.nih.gov/29900173/PubMed (2018): Herpes zoster and UV exposure: Mechanisms and implications:https://pubmed.ncbi.nlm.nih.gov/30506967/PubMed (2019): The human skin microbiome in health and disease:https://pubmed.ncbi.nlm.nih.gov/31883695/PubMed (2020): Microbiome dysbiosis and immune response in herpesvirus infections:https://pubmed.ncbi.nlm.nih.gov/33237617/PubMed (2021): Skin microbiome disruption and viral reactivation:https://pubmed.ncbi.nlm.nih.gov/33733653/PubMed (2024): Skin microbiota's role in reactivation of herpes zoster under UV stress:https://pubmed.ncbi.nlm.nih.gov/40238652/#Shingles #VZV #UltravioletRadiation #Microbiome #SkinMicrobiome #ImmuneSuppression #HerpesZoster #skinhealth #MedicalResearch #DermUpdate #SkinScience #Dermatology #DermatologyProvider #Dermatologist #CosmeticDermatology #Aesthetics #PhysicianAssistant #PhysicianAssociate #NursePractitioner #SkinfluencedPodcast #DermatologyPodcast

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