For the first time ever we’ve used CRISPR  to edit someone’s genes INSIDE THEIR BODY! So far we’ve been able to reverse some effects of rare genetic eye disease that results in blindness, and this is only the beginning!

You can WATCH the podcast over on our YouTube channel:
http://youtube.com/SciGuys



Help keep the show running by supporting us on Patreon!
http://patreon.com/sciguys



If you'd like to see more of us, follow our socials!

Facebook
http://facebook.com/SciGuysPod

Twitter
http://twitter.com/SciGuysPod

Instagram
http://instagram.com/SciGuysPod

Follow the SCI GUYS
@notcorry / @jampkin / @lukecutforth


References & Further Reading




https://medlineplus.gov/genetics/condition/leber-congenital-amaurosis/
https://rarediseases.info.nih.gov/diseases/634/leber-congenital-amaurosis
https://luxturna.com



Gene Therapy

https://www.nature.com/articles/d41586-018-06195-6
https://www.nature.com/articles/s41587-020-0493-4
https://www.nature.com/articles/s41573-019-0012-9



The EDIT-101 Trial

https://clinicaltrials.gov/ct2/show/study/NCT03872479
https://www.nature.com/articles/s41591-018-0327-9
https://text.npr.org/2021/09/29/1040879179/vision-loss-crispr-treatment
https://www.nature.com/articles/d41586-020-00655-8https://www.nature.com/articles/d41586-020-00655-8
https://jamanetwork.com/journals/jama/fullarticle/2764428https://jamanetwork.com/journals/jama/fullarticle/2764428

Ver todos los episodios