Green-top Guideline no. 74 Antenatal corticosteroids to reduce neonatal morbidity and mortality

17/02/2022 1h 42min
Green-top Guideline no. 74 Antenatal corticosteroids to reduce neonatal morbidity and mortality

Listen "Green-top Guideline no. 74 Antenatal corticosteroids to reduce neonatal morbidity and mortality"

Episode Synopsis

The aim of this guideline is to provide evidence-based recommendations on the use of antenatal corticosteroids in women at risk of preterm birth or undergoing caesarean birth at term.

1: Key Recommendations (00:50)
2: Background and Scope (03:46 )
3: Identification and Assessment of Evidence (06:27)
4: The Benefits of Antenatal Corticosteroids (07:30)
4.1: What are the benefits of corticosteroids in preterm labour and birth (07:35)
4.2 What are the benefits of corticosteroids in planned caesarean birth at term (10:04)
Table 1: Risks and benefits of antenatal corticosteroids to be discussed and offered (16:46)
5: At what gestation should antenatal corticosteroids be discussed and offered (27:03)
6: In what particular circumstances would antenatal corticosteroids be discussed with and offered to women? (34:43)
6.1: Multiple pregnancy (34:54)
6.2 Women with diabetes mellitus (39:03)
6.3 Pregnancies complicated by fetal growth restriction, pre-eclampsia or antepartum haemorrhage (43:11)
6.4. Preterm, prelabour rupture of membranes (PPROM) (51:17)
7: What is the optimum dose and route of administration for a course of antenatal corticosteroids? (55:46)
Betamethasone (58:44 )
Dexamethasone (1:01:00)
8: How long after administration is a course of antenatal corticosteroids most effective? (1:05:40)
9: What are the risks associated with the administration of antenatal corticosteroids? (1:17:50)
9.1: What are the risks to the woman? (1:19:00)
9.2: What are the risks to the baby? (1:20:53)
10 - What are the contraindications to the use of antenatal corticosteroids? (1:31:44 )
11 - In what circumstances should an antenatal course of corticosteroids be repeated? (1:33:31)
12. Recommendations for future research (1:37:21)
13. Auditable topics (1:38:37)
Closing Statement (1:39:52)

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