In this episode of the JGO Podcast, we explore a recent study from Peking Union Medical College Hospital examining the role of adjuvant surgery in patients with high-risk chemorefractory or relapsed gestational choriocarcinoma who achieve complete remission following anti-PD-1 therapy. The retrospective analysis of 43 patients reveals no significant difference in survival outcomes between those who underwent surgery and those who did not, raising important questions about the necessity of surgical intervention in this setting. We discuss the implications of these findings in light of current treatment guidelines and emerging data on immunotherapy in gestational trophoblastic neoplasia.

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