Zerlasiran, a Small-Interfering RNA That Targets Lipoprotein(a)

18/11/2024 14 min
Zerlasiran, a Small-Interfering RNA That Targets Lipoprotein(a)

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Episode Synopsis

Elevated lipoprotein(a) levels increase the risk of atherosclerotic cardiovascular disease (ASCVD) and aortic stenosis. Cleveland Clinic's Steven E. Nissen, MD, speaks with JAMA Executive Editor Gregory Curfman, MD, about how zerlasiran produced more than 80% reductions in time-averaged lipoprotein(a) concentration. Related Content: Zerlasiran—A Small-Interfering RNA Targeting Lipoprotein(a)

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