SummaryIn episode 9, Drs. Grant and Ziva Cooper discuss her research on medicinal cannabis, focusing on gender differences in cannabis response, the therapeutic potential of minor cannabinoids and terpenes, and the opioid-sparing effects of cannabinoids. The conversation highlights the complexities of cannabis research, including regulatory challenges and the need for further studies to clarify the role of cannabinoids in medicine.Takeaways• Dr. Ziva Cooper is a leading researcher in medicinal cannabis.• Gender differences in cannabis response are significant.• Women may be more sensitive to the pain-relieving effects of cannabis.• Minor cannabinoids like CBG show promise for therapeutic use.• Terpenes may enhance the effects of THC without psychoactivity.• Cannabinoids could potentially reduce opioid use in chronic pain patients.• Research on cannabinoids faces significant regulatory hurdles.• Understanding the psychological aspects of pain is crucial.• The therapeutic potential of cannabinoids is still being explored.• Future research is needed to clarify the role of cannabinoids in medicine.Chapters00:00 CBG for Pain and Appetite Stimulation00:51 Exploring Sex Differences in Cannabis Response00:52 Intro01:24 Understanding Cannabinoids: THC, CBD, and Beyond01:24 Introduction to Ziva Cooper, PhD02:17 THC and Sex and Gender Differences11:09 Minor Cannabinoids, Terpenes and Terpenoids13:46 Cannabigerol (CBG) for Pain and Appetite Stimulation20:21 Cannabichromine for Pain21:48 Exploring Cannabichromine (CBC) and Its Potential22:21 Understanding Terpenes and Terpendoids (Myrcene and Beta-Caryophyllene)24:46 The Different Regulatory Status of Terpenes and Terpenoids26:04 Cannabinoids as Opioid-Sparing Agents30:22 Cannabinoids and Substance Use Disorders32:04 The Psychological Experience of Pain35:14 Advancing Cannabinoid Research in Medicine38:10 Regulatory Hurdles to Researching Cannabis and Cannabinoids40:16 Outro

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