Dr. K breaks down how psychedelics actually work not from hype or hearsay, but through neuroscience, psychiatry, and lived experience. He explains that psychedelics don’t “heal” you by themselves; they temporarily put the brain into edit mode, a state of heightened neuroplasticity where your thoughts, emotions, and physiology can be rewritten for better or worse.

Through a detailed look at serotonin receptors, brain connectivity, and decades of clinical research, Dr. K shows how substances like psilocybin, LSD, DMT, ayahuasca, and MDMA can rewire the brain and why they can just as easily cause harm if used without structure, safety, or integration. The episode also explores why guided psychedelic therapy — in a clinical or spiritual context — can lead to long-term healing, while unsupervised trips can lock trauma in even deeper.

Dr. K ties it all together by connecting ego death to meditation and Vedic philosophy, revealing how both psychedelics and deep meditative practice dissolve the sense of self — and why that dissolution is often the real mechanism of healing.

Topics include:




The serotonin 2A receptor and why psychedelics increase neuroplasticity and neurogenesis




How “edit mode” rewires your brain and how it can backfire




Why integration therapy is critical after a psychedelic experience




Set and setting: the real difference between healing and harm




Which psychedelics work best for depression, PTSD, and addiction




Why microdosing feels good but may not create long-term change




The role of ego death and why it mirrors advanced meditation experiences




Psychedelics vs. antidepressants - what the data actually says about efficacy and risk



This episode is a deep dive into the science, safety, and spirituality of psychedelics offering clarity in a space often clouded by hype, myth, and misinformation.


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