Week 10 of the 2025 fantasy football season is upon us, and for managers everywhere, finding the right defensive/special teams (D/ST) to start is crucial for securing a win. This week, several matchups present great opportunities for fantasy points from D/STs, and experts across various platforms have updated their rankings to guide you in setting your lineups.One of the best options this week is the Denver Broncos, who are set to face the Las Vegas Raiders. The Broncos' defense has been consistent, and their matchup against the Raiders, who have struggled offensively, could mean a big scoring day for fantasy managers who take advantage of this matchup.The Cleveland Browns are another team that should be on your radar as they go up against the New York Jets. The Browns' defense has shown strength and versatility, and facing a Jets team that has been inconsistent on offense improves their chances to rack up sacks and turnovers, all of which translate to valuable fantasy points.For those looking for a sleeper pick, the Detroit Lions are an intriguing option. They will be facing the Washington Commanders, a team with vulnerabilities that a strategic defense like the Lions can exploit. The Lions have been steadily improving on defense and could provide a surprising boost to your fantasy lineup.It's also an excellent time to review your overall strategy and consider adding depth to your roster based on Week 10 rankings for other positions. FantraxHQ has highlighted some key players that could be valuable additions via the waiver wire. Picking up and holding these players could be pivotal in the long term, especially as the fantasy playoffs approach.The QB List has also released its updated top 150 FLEX and positional rankings for Week 10, which highlight players to consider for optimizing your lineup. Staying informed with these rankings will help you make decisions that align with current trends and player performances.Incorporating the insights from USA Today, FantraxHQ, and the QB List can give you a competitive edge, ensuring your D/ST and overall lineup are primed for success this Week 10. Adjust your strategies accordingly and keep an eye on the rankings for the best chance of clinching a win in this crucial stretch of the fantasy football season.This content was created in partnership and with the help of Artificial Intelligence AI

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