Listen "Onc Now: Episode 24: What Will the Next Decade of HER2-Targeted Therapy Look Like?"
Episode Synopsis
In this episode of Onc Now, host Jonathan Sackier welcomes Komal Jhaveri, Breast Medical Oncologist and clinical investigator at Memorial Sloan Kettering Cancer Center, New York, USA. Known for her trailblazing work in HER2-positive, HER2-low, and hormone receptor-positive breast cancers, Komal Jhaveri discusses how molecular subtyping, antibody-drug conjugates, and precision trials are reshaping the field. Timestamps 00:00 – Introduction 02:50 – What initially drew Komal into oncology 04:45 – The future of breast cancer care 06:13 – Possibility of personalised treatments for patients 07:40 – Antibody-drug conjugates 09:30 – How we define HER2 status 14:40 – HER2-low disease 17:40 – Targeted therapy combinations 20:54 – Endocrine resistance 23:18 – The realities of implementing new therapies 28:40 – Promising initiatives on the horizon 31:30 – Komal's key takeaways
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