Cellular Signals, Episode 2: "From Foreign to Familiar - The Mitochondrial Saga"
Dive into the intriguing tale of mitochondria, the powerhouses of our
cells. Once autonomous entities, these cellular components now play a
critical role in our energy production. But hints of their foreign
origins still linger in our cellular mechanics. In this episode, we
unravel the mystery of how an ancient partnership between a
proto-eukaryote and a ɑ-proteobacterium laid the foundation for complex
life. We'll explore the delicate dance of biogenesis, xenophagy, and
mitophagy, while shedding light on the enduring sense of "foreignness"
that our cells retain towards mitochondria. Join us as we trace the
evolution of this ancient relationship and discover the remarkable
cellular processes that have evolved to maintain this balance.

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