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Listen "AI Predicts Post-Infarct Arrhythmia Risk 09/20/25"
Episode Synopsis
Welcome to Cardiology Today – Recorded September 20, 2025. This episode summarizes 5 key cardiology studies on topics like artificial intelligence and N-Formylmethionine. Key takeaway: AI Predicts Post-Infarct Arrhythmia Risk.
Article Links:
Article 1: Explainable Artificial Intelligence-Driven Risk Assessment for Malignant Ventricular Arrhythmia and Mortality in Acute Myocardial Infarction. (The Canadian journal of cardiology)
Article 2: Plasma Metabolite N-Formylmethionine Is Associated With Higher Blood Pressure in the Multiethnic HELIUS Cohort and Triggers Vascular Dysfunction. (Hypertension (Dallas, Tex. : 1979))
Article 3: Neutrophil Extracellular Traps and Delayed Cerebral Ischemia in Patients With Subarachnoid Hemorrhage. (Journal of the American Heart Association)
Article 4: Rationale and Design of the EPISODE Trial: A Randomized Controlled Trial on the Effect of PCSK9 Inhibitors in Calcific Aortic Valve Stenosis. (Journal of the American Heart Association)
Article 5: Left Ventricular Mass-to-Strain Ratio to Predict Change in Left Ventricular Hypertrophy and Prognosis in Hypertensive Heart Disease. (Journal of the American Heart Association)
Full episode page: https://podcast.explainheart.com/podcast/ai-predicts-post-infarct-arrhythmia-risk-09-20-25/
Featured Articles
Article 1: Explainable Artificial Intelligence-Driven Risk Assessment for Malignant Ventricular Arrhythmia and Mortality in Acute Myocardial Infarction.
Journal: The Canadian journal of cardiology
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40972895
Summary: This study developed artificial intelligence models to predict malignant ventricular arrhythmia and in-hospital death after acute myocardial infarction using data from 4,471 patients. The models demonstrated predictive performance, suggesting artificial intelligence could be a valuable tool for risk stratification in patients post myocardial infarction. Further prospective validation is needed to confirm these findings.
Article 2: Plasma Metabolite N-Formylmethionine Is Associated With Higher Blood Pressure in the Multiethnic HELIUS Cohort and Triggers Vascular Dysfunction.
Journal: Hypertension (Dallas, Tex. : 1979)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40959884
Summary: In a multiethnic cohort study, the plasma metabolite N-Formylmethionine was associated with higher blood pressure. This association suggests a potential link between N-Formylmethionine and vascular dysfunction across diverse ethnic groups. Further research is needed to explore N-Formylmethionine as a therapeutic target for hypertension.
Article 3: Neutrophil Extracellular Traps and Delayed Cerebral Ischemia in Patients With Subarachnoid Hemorrhage.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40970545
Summary: This prospective single-center study investigated the role of neutrophil extracellular traps in delayed cerebral ischemia following subarachnoid hemorrhage. The study found an association between trajectories of neutrophil extracellular trap biomarkers and the occurrence of delayed cerebral ischemia. These findings suggest that neutrophil extracellular traps may be a therapeutic target for preventing delayed cerebral ischemia in patients with subarachnoid hemorrhage.
Article 4: Rationale and Design of the EPISODE Trial: A Randomized Controlled Trial on the Effect of PCSK9 Inhibitors in Calcific Aortic Valve Stenosis.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40970544
Summary: The EPISODE trial is a randomized controlled trial designed to investigate the effect of Proprotein Convertase Subtilisin/Kexin Type 9 inhibitors on calcific aortic valve stenosis. This trial aims to determine if Proprotein Convertase Subtilisin/Kexin Type 9 inhibition can prevent or delay the progression of calcific aortic valve stenosis, addressing the current lack of effective pharmacological interventions. The trial is ongoing.
Article 5: Left Ventricular Mass-to-Strain Ratio to Predict Change in Left Ventricular Hypertrophy and Prognosis in Hypertensive Heart Disease.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40970541
Summary: This retrospective study evaluated the left ventricular mass-to-strain ratio as a marker of the clinical course in patients with hypertensive heart disease. The study found that the left ventricular mass-to-strain ratio can predict changes in left ventricular hypertrophy and prognosis in these patients. The findings suggest that the left ventricular mass-to-strain ratio is a valuable tool for risk stratification and monitoring disease progression in hypertensive heart disease.
Transcript
Today’s date is September 20, 2025. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Explainable Artificial Intelligence-Driven Risk Assessment for Malignant Ventricular Arrhythmia and Mortality in Acute Myocardial Infarction. This study developed artificial intelligence models to predict malignant ventricular arrhythmia and in-hospital death after acute myocardial infarction using data from 4,471 patients. The models demonstrated predictive performance, suggesting artificial intelligence could be a valuable tool for risk stratification in patients post myocardial infarction. Further prospective validation is needed to confirm these findings.
Article number two. Plasma Metabolite N-Formylmethionine Is Associated With Higher Blood Pressure in the Multiethnic HELIUS Cohort and Triggers Vascular Dysfunction. In a multiethnic cohort study, the plasma metabolite N-Formylmethionine was associated with higher blood pressure. This association suggests a potential link between N-Formylmethionine and vascular dysfunction across diverse ethnic groups. Further research is needed to explore N-Formylmethionine as a therapeutic target for hypertension.
Article number three. Neutrophil Extracellular Traps and Delayed Cerebral Ischemia in Patients With Subarachnoid Hemorrhage. This prospective single-center study investigated the role of neutrophil extracellular traps in delayed cerebral ischemia following subarachnoid hemorrhage. The study found an association between trajectories of neutrophil extracellular trap biomarkers and the occurrence of delayed cerebral ischemia. These findings suggest that neutrophil extracellular traps may be a therapeutic target for preventing delayed cerebral ischemia in patients with subarachnoid hemorrhage.
Article number four. Rationale and Design of the EPISODE Trial: A Randomized Controlled Trial on the Effect of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors in Calcific Aortic Valve Stenosis. The EPISODE trial is a randomized controlled trial designed to investigate the effect of Proprotein Convertase Subtilisin/Kexin Type 9 inhibitors on calcific aortic valve stenosis. This trial aims to determine if Proprotein Convertase Subtilisin/Kexin Type 9 inhibition can prevent or delay the progression of calcific aortic valve stenosis, addressing the current lack of effective pharmacological interventions. The trial is ongoing.
Article number five. Left Ventricular Mass-to-Strain Ratio to Predict Change in Left Ventricular Hypertrophy and Prognosis in Hypertensive Heart Disease. This retrospective study evaluated the left ventricular mass-to-strain ratio as a marker of the clinical course in patients with hypertensive heart disease. The study found that the left ventricular mass-to-strain ratio can predict changes in left ventricular hypertrophy and prognosis in these patients. The findings suggest that the left ventricular mass-to-strain ratio is a valuable tool for risk stratification and monitoring disease progression in hypertensive heart disease.
Thank you for listening. Don’t forget to subscribe.
Keywords
artificial intelligence, N-Formylmethionine, plasma metabolites, delayed cerebral ischemia, echocardiography, blood pressure, global longitudinal strain, left ventricular mass-to-strain ratio, neutrophil extracellular traps, lipoprotein (a), vascular dysfunction, hypertension, NET biomarkers, hypertensive heart disease, left ventricular hypertrophy, acute myocardial infarction, malignant ventricular arrhythmia, clinical trial, calcific aortic valve stenosis, Proprotein Convertase Subtilisin/Kexin Type 9 inhibitors, sudden cardiac death, risk assessment, immunothrombosis, low-density lipoprotein cholesterol, subarachnoid hemorrhage.
About
Concise summaries of cardiovascular research for professionals.
Subscribe • Share • FollowThe post AI Predicts Post-Infarct Arrhythmia Risk 09/20/25 first appeared on Cardiology Today.
Article Links:
Article 1: Explainable Artificial Intelligence-Driven Risk Assessment for Malignant Ventricular Arrhythmia and Mortality in Acute Myocardial Infarction. (The Canadian journal of cardiology)
Article 2: Plasma Metabolite N-Formylmethionine Is Associated With Higher Blood Pressure in the Multiethnic HELIUS Cohort and Triggers Vascular Dysfunction. (Hypertension (Dallas, Tex. : 1979))
Article 3: Neutrophil Extracellular Traps and Delayed Cerebral Ischemia in Patients With Subarachnoid Hemorrhage. (Journal of the American Heart Association)
Article 4: Rationale and Design of the EPISODE Trial: A Randomized Controlled Trial on the Effect of PCSK9 Inhibitors in Calcific Aortic Valve Stenosis. (Journal of the American Heart Association)
Article 5: Left Ventricular Mass-to-Strain Ratio to Predict Change in Left Ventricular Hypertrophy and Prognosis in Hypertensive Heart Disease. (Journal of the American Heart Association)
Full episode page: https://podcast.explainheart.com/podcast/ai-predicts-post-infarct-arrhythmia-risk-09-20-25/
Featured Articles
Article 1: Explainable Artificial Intelligence-Driven Risk Assessment for Malignant Ventricular Arrhythmia and Mortality in Acute Myocardial Infarction.
Journal: The Canadian journal of cardiology
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40972895
Summary: This study developed artificial intelligence models to predict malignant ventricular arrhythmia and in-hospital death after acute myocardial infarction using data from 4,471 patients. The models demonstrated predictive performance, suggesting artificial intelligence could be a valuable tool for risk stratification in patients post myocardial infarction. Further prospective validation is needed to confirm these findings.
Article 2: Plasma Metabolite N-Formylmethionine Is Associated With Higher Blood Pressure in the Multiethnic HELIUS Cohort and Triggers Vascular Dysfunction.
Journal: Hypertension (Dallas, Tex. : 1979)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40959884
Summary: In a multiethnic cohort study, the plasma metabolite N-Formylmethionine was associated with higher blood pressure. This association suggests a potential link between N-Formylmethionine and vascular dysfunction across diverse ethnic groups. Further research is needed to explore N-Formylmethionine as a therapeutic target for hypertension.
Article 3: Neutrophil Extracellular Traps and Delayed Cerebral Ischemia in Patients With Subarachnoid Hemorrhage.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40970545
Summary: This prospective single-center study investigated the role of neutrophil extracellular traps in delayed cerebral ischemia following subarachnoid hemorrhage. The study found an association between trajectories of neutrophil extracellular trap biomarkers and the occurrence of delayed cerebral ischemia. These findings suggest that neutrophil extracellular traps may be a therapeutic target for preventing delayed cerebral ischemia in patients with subarachnoid hemorrhage.
Article 4: Rationale and Design of the EPISODE Trial: A Randomized Controlled Trial on the Effect of PCSK9 Inhibitors in Calcific Aortic Valve Stenosis.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40970544
Summary: The EPISODE trial is a randomized controlled trial designed to investigate the effect of Proprotein Convertase Subtilisin/Kexin Type 9 inhibitors on calcific aortic valve stenosis. This trial aims to determine if Proprotein Convertase Subtilisin/Kexin Type 9 inhibition can prevent or delay the progression of calcific aortic valve stenosis, addressing the current lack of effective pharmacological interventions. The trial is ongoing.
Article 5: Left Ventricular Mass-to-Strain Ratio to Predict Change in Left Ventricular Hypertrophy and Prognosis in Hypertensive Heart Disease.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40970541
Summary: This retrospective study evaluated the left ventricular mass-to-strain ratio as a marker of the clinical course in patients with hypertensive heart disease. The study found that the left ventricular mass-to-strain ratio can predict changes in left ventricular hypertrophy and prognosis in these patients. The findings suggest that the left ventricular mass-to-strain ratio is a valuable tool for risk stratification and monitoring disease progression in hypertensive heart disease.
Transcript
Today’s date is September 20, 2025. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Explainable Artificial Intelligence-Driven Risk Assessment for Malignant Ventricular Arrhythmia and Mortality in Acute Myocardial Infarction. This study developed artificial intelligence models to predict malignant ventricular arrhythmia and in-hospital death after acute myocardial infarction using data from 4,471 patients. The models demonstrated predictive performance, suggesting artificial intelligence could be a valuable tool for risk stratification in patients post myocardial infarction. Further prospective validation is needed to confirm these findings.
Article number two. Plasma Metabolite N-Formylmethionine Is Associated With Higher Blood Pressure in the Multiethnic HELIUS Cohort and Triggers Vascular Dysfunction. In a multiethnic cohort study, the plasma metabolite N-Formylmethionine was associated with higher blood pressure. This association suggests a potential link between N-Formylmethionine and vascular dysfunction across diverse ethnic groups. Further research is needed to explore N-Formylmethionine as a therapeutic target for hypertension.
Article number three. Neutrophil Extracellular Traps and Delayed Cerebral Ischemia in Patients With Subarachnoid Hemorrhage. This prospective single-center study investigated the role of neutrophil extracellular traps in delayed cerebral ischemia following subarachnoid hemorrhage. The study found an association between trajectories of neutrophil extracellular trap biomarkers and the occurrence of delayed cerebral ischemia. These findings suggest that neutrophil extracellular traps may be a therapeutic target for preventing delayed cerebral ischemia in patients with subarachnoid hemorrhage.
Article number four. Rationale and Design of the EPISODE Trial: A Randomized Controlled Trial on the Effect of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors in Calcific Aortic Valve Stenosis. The EPISODE trial is a randomized controlled trial designed to investigate the effect of Proprotein Convertase Subtilisin/Kexin Type 9 inhibitors on calcific aortic valve stenosis. This trial aims to determine if Proprotein Convertase Subtilisin/Kexin Type 9 inhibition can prevent or delay the progression of calcific aortic valve stenosis, addressing the current lack of effective pharmacological interventions. The trial is ongoing.
Article number five. Left Ventricular Mass-to-Strain Ratio to Predict Change in Left Ventricular Hypertrophy and Prognosis in Hypertensive Heart Disease. This retrospective study evaluated the left ventricular mass-to-strain ratio as a marker of the clinical course in patients with hypertensive heart disease. The study found that the left ventricular mass-to-strain ratio can predict changes in left ventricular hypertrophy and prognosis in these patients. The findings suggest that the left ventricular mass-to-strain ratio is a valuable tool for risk stratification and monitoring disease progression in hypertensive heart disease.
Thank you for listening. Don’t forget to subscribe.
Keywords
artificial intelligence, N-Formylmethionine, plasma metabolites, delayed cerebral ischemia, echocardiography, blood pressure, global longitudinal strain, left ventricular mass-to-strain ratio, neutrophil extracellular traps, lipoprotein (a), vascular dysfunction, hypertension, NET biomarkers, hypertensive heart disease, left ventricular hypertrophy, acute myocardial infarction, malignant ventricular arrhythmia, clinical trial, calcific aortic valve stenosis, Proprotein Convertase Subtilisin/Kexin Type 9 inhibitors, sudden cardiac death, risk assessment, immunothrombosis, low-density lipoprotein cholesterol, subarachnoid hemorrhage.
About
Concise summaries of cardiovascular research for professionals.
Subscribe • Share • FollowThe post AI Predicts Post-Infarct Arrhythmia Risk 09/20/25 first appeared on Cardiology Today.
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