Everyone has down days and times of feeling sad or blue, but people living with MS have more than their fair share. In fact, the rate of clinical depression is higher in MS than in the general population, as well as higher than in most chronic illnesses. The numbers are similar to those seen in other neuro-inflammatory diseases (e.g., rheumatoid arthritis and inflammatory bowel disease), suggesting that the inflammation itself plays a role, along with changes in the brain and the psychosocial challenges of living with a challenging, unpredictable illness. Today, we know that depression is one of the most common symptoms of MS. Like all of the other symptoms of MS, it deserves to be diagnosed quickly and treated effectively. The good news is that depression is very treatable.

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