Send us a text🧠 Clinical Context:BBs have been MI standard since the thrombolysis era.But do they still help when patients get PCI, statins, and ACEs?🧪 Two Major Studies:Swedish Registry Study:Post-MI patients with preserved EF.All received PCI + standard meds.BB vs no BB: No difference in death or recurrent MI.French Study (New England Journal):MI 2.9 years prior, preserved EF.BB continuation vs discontinuation:Slight reduction in composite endpoint (death/MI/stroke/hospitalization).Driven mostly by fewer hospitalizations (17% vs 19%).⚖️ Pros and Cons of Beta Blockers:✅ Pro: Cardioprotection, arrhythmia prevention.❌ Con: Depression, fatigue, ED, bradycardia.BBs aren’t benign — side effects matter to patients.🧩 Clinical Pearls:If EF is normal and patient is stable post-MI: Reassess need for long-term BB.Ongoing trials will help guide “de-prescription” thresholds.Don't forget individualized care: patient preference, arrhythmia risk, BP goals.

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