Send us a text🧠 Context:Rising rates of carbapenem-resistant gram-negatives, especially those producing MBLs like NDM, VIM.💊 Drug Combo:Aztreonam + Avibactam = a lifeline for metallo-beta-lactamase (MBL) producers.FDA-approved for:Complicated intra-abdominal infections (with metronidazole).Hospital-acquired and ventilator-associated pneumonias (HAP/VAP).🧩 Clinical Takeaway:Reserved for pan-resistant infections; not a first-line agent.ID consult required in most hospitals due to high cost and restricted use.This is your last-resort ammo — know when to reach for it.

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