🎙️ Episode 10: Colchicine & Diabetes: The Unsung Hero Post-MI?

Brilliant Board Review & CME
20/04/2025 1 min Temporada 1 Episodio 10
🎙️ Episode 10: Colchicine & Diabetes: The Unsung Hero Post-MI?

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Episode Synopsis

Send us a text🧠 Clinical Background:Inflammation plays a big role in atherothrombosis.Colchicine — an old gout drug — shows promise in CV risk reduction.🧪 COLCOT Trial:Colchicine 0.5 mg daily post-MI.Greatest benefit in patients with type 2 diabetes.📈 Outcomes:Reduced MACE (MI, stroke, death) in diabetics.Adverse Effects: Nausea, diarrhea, ↑ risk of pneumonia (unclear why).🧩 Clinical Takeaway:Consider colchicine in diabetics post-MI or with recurrent ACS.Cheap, oral, and anti-inflammatory — a new use for an old drug.

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