The Interferon I role in autoimmune disease and the corruption of mechanisms that lead to age-related morbidity and mortality.DJGPhD. 22.9.21

Authentic Biochemistry
22/09/2021 30 min

Listen "The Interferon I role in autoimmune disease and the corruption of mechanisms that lead to age-related morbidity and mortality.DJGPhD. 22.9.21"

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Episode Synopsis

Interferons are innate immune agents of inflammation and recovery. Mutations or epigenetic modifications associated with advanced aging may corrupt interferon pathway  fidelity involving mitophagy leading to autoimmune disease and morbidity later in life.
References
Nat Immunol. 2021 Mar; 22(3): 312–321
J Neuroinflammation. 2019; 16: 236.


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