Stanford Medcast Episode 107: Hot Topics Mini-Series: Gut Check - How the Microbiome Shapes CAR-T Therapy Outcomes

12/08/2025 29 min
Stanford Medcast Episode 107: Hot Topics Mini-Series: Gut Check - How the Microbiome Shapes CAR-T Therapy Outcomes

Listen "Stanford Medcast Episode 107: Hot Topics Mini-Series: Gut Check - How the Microbiome Shapes CAR-T Therapy Outcomes"

Episode Synopsis

The microbiome is emerging as a key player in the effectiveness of CAR-T therapy, and today, Dr. Melody Smith, Assistant Professor of Medicine at Stanford University, sheds light on this fascinating intersection. Join us as we explore how advancements in CAR T-cell therapy are reshaping patient demographics and treatment approaches. Dr. Smith will discuss the implications of genetic engineering techniques like CRISPR, the importance of a multidisciplinary treatment strategy, and the role of antibiotic stewardship in optimizing outcomes. With insights into innovative therapies and ongoing clinical trials, this conversation promises to deepen your understanding of CAR-T therapy and its complexities, offering a glimpse into the future of cancer treatment.

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