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Listen "Episode 16: Giuseppe Orlando, MD, PhD, Marie Curie Fellow, Associate Professor at the Wake Forest University School of Medicine"
Episode Synopsis
In this episode, Dr. Giuseppe Orlando joins Monica Westley to discuss his interest in type 1 diabetes and strategies for pancreas transplantation. Dr. Orlando is a kidney and pancreas transplant surgeon at the Wake Forest University School of Medicine.
Dr. Orlando- "The problem of using the whole pancreas as a scaffold actually entails the same problems that full organ bioengineering puts us in front of. Which is that we can't replicate the vasculature of an organ. Research is shifting towards to a different approach, you still decellularize the whole organ but then you chop the organ and convert the extracellular matrix into a hydrogel."
Dr. Orlando- "The problem of using the whole pancreas as a scaffold actually entails the same problems that full organ bioengineering puts us in front of. Which is that we can't replicate the vasculature of an organ. Research is shifting towards to a different approach, you still decellularize the whole organ but then you chop the organ and convert the extracellular matrix into a hydrogel."
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