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Listen "Aortic Dilation: New Predictors of Rapid Progression 09/14/25"
Episode Synopsis
Welcome to Cardiology Today – Recorded September 14, 2025. This episode summarizes 5 key cardiology studies on topics like computed tomography and right ventricle. Key takeaway: Aortic Dilation: New Predictors of Rapid Progression.
Article Links:
Article 1: Vascular endothelial growth factor inhibitor-induced cardiotoxicity: prospective multimodality assessment incorporating cardiovascular magnetic resonance imaging. (Heart (British Cardiac Society))
Article 2: Synergistic effects of female-specific conditions and genetic risk on cardiometabolic disease: a cohort study. (Heart (British Cardiac Society))
Article 3: Follow-up of incidentally detected mild to moderate ascending aortic dilation and risk factors for rapid progression in a Swedish middle-aged population. (Heart (British Cardiac Society))
Article 4: Percutaneous intramyocardial septal radiofrequency ablation: a novel treatment for drug-refractory non-obstructive hypertrophic cardiomyopathy with severe septal hypertrophy. (Heart (British Cardiac Society))
Article 5: Relationship Between Electrical and Morphological Alterations of the Right Ventricle in Arrhythmogenic Right Ventricular Cardiomyopathy. (Heart rhythm)
Full episode page: https://podcast.explainheart.com/podcast/aortic-dilation-new-predictors-of-rapid-progression-09-14-25/
Featured Articles
Article 1: Vascular endothelial growth factor inhibitor-induced cardiotoxicity: prospective multimodality assessment incorporating cardiovascular magnetic resonance imaging.
Journal: Heart (British Cardiac Society)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40180444
Summary: This study prospectively evaluated cardiotoxicity in patients receiving vascular endothelial growth factor inhibitors for cancer treatment, utilizing blood pressure monitoring, echocardiography, and cardiac biomarkers. The research aims to define the incidence, time course, and mechanisms of vascular endothelial growth factor inhibitor associated cancer therapy-related cardiac dysfunction and hypertension through a multi-modal approach including cardiovascular magnetic resonance imaging. The study is ongoing and will provide insights into early detection and management of cardiotoxicity in this patient population.
Article 2: Synergistic effects of female-specific conditions and genetic risk on cardiometabolic disease: a cohort study.
Journal: Heart (British Cardiac Society)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40139682
Summary: This prospective cohort study of over 150,000 women from the United Kingdom Biobank examined the association between female-specific factors like premature menopause, adverse pregnancy outcomes, and early or late menarche, and the occurrence and progression of cardiometabolic disease. The study aims to determine how these factors interact with genetic risk to influence cardiometabolic health in women. Understanding these interactions will help refine risk stratification and prevention strategies for cardiometabolic disease in women.
Article 3: Follow-up of incidentally detected mild to moderate ascending aortic dilation and risk factors for rapid progression in a Swedish middle-aged population.
Journal: Heart (British Cardiac Society)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40081936
Summary: This study investigated the progression of incidentally detected mild to moderate ascending aortic dilation in a Swedish population aged 50-65 years. Researchers followed over 5,000 participants to identify risk factors associated with rapid aortic dilation, which can lead to life-threatening aortic syndromes. Identifying these risk factors will refine surveillance strategies and potentially guide preventive interventions for aortic aneurysm.
Article 4: Percutaneous intramyocardial septal radiofrequency ablation: a novel treatment for drug-refractory non-obstructive hypertrophic cardiomyopathy with severe septal hypertrophy.
Journal: Heart (British Cardiac Society)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40054888
Summary: This single-arm, open-label study evaluated the safety and effectiveness of percutaneous intramyocardial septal radiofrequency ablation for drug-refractory non-obstructive hypertrophic cardiomyopathy patients with severe septal hypertrophy. Twenty patients underwent the procedure, with follow-up assessments to determine the impact on symptoms and cardiac function. Percutaneous intramyocardial septal radiofrequency ablation offers a new invasive treatment option for this challenging patient population.
Article 5: Relationship Between Electrical and Morphological Alterations of the Right Ventricle in Arrhythmogenic Right Ventricular Cardiomyopathy.
Journal: Heart rhythm
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40945559
Summary: This retrospective study investigated the spatial relationship between low-voltage areas detected during electrophysiological mapping and morphofunctional abnormalities seen on computed tomography imaging in patients with arrhythmogenic right ventricular cardiomyopathy. The right ventricle was divided into seven regions, and the correlation between electrical and structural changes was analyzed. Understanding this relationship may improve the targeting of ventricular tachycardia ablation and risk stratification in arrhythmogenic right ventricular cardiomyopathy.
Transcript
Today’s date is September 14, 2025. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Vascular endothelial growth factor inhibitor-induced cardiotoxicity: prospective multimodality assessment incorporating cardiovascular magnetic resonance imaging. This study prospectively evaluated cardiotoxicity in patients receiving vascular endothelial growth factor inhibitors for cancer treatment, utilizing blood pressure monitoring, echocardiography, and cardiac biomarkers. The research aims to define the incidence, time course, and mechanisms of vascular endothelial growth factor inhibitor associated cancer therapy-related cardiac dysfunction and hypertension through a multi-modal approach including cardiovascular magnetic resonance imaging. The study is ongoing and will provide insights into early detection and management of cardiotoxicity in this patient population.
Article number two. Synergistic effects of female-specific conditions and genetic risk on cardiometabolic disease: a cohort study. This prospective cohort study of over 150,000 women from the United Kingdom Biobank examined the association between female-specific factors like premature menopause, adverse pregnancy outcomes, and early or late menarche, and the occurrence and progression of cardiometabolic disease. The study aims to determine how these factors interact with genetic risk to influence cardiometabolic health in women. Understanding these interactions will help refine risk stratification and prevention strategies for cardiometabolic disease in women.
Article number three. Follow-up of incidentally detected mild to moderate ascending aortic dilation and risk factors for rapid progression in a Swedish middle-aged population. This study investigated the progression of incidentally detected mild to moderate ascending aortic dilation in a Swedish population aged 50-65 years. Researchers followed over 5,000 participants to identify risk factors associated with rapid aortic dilation, which can lead to life-threatening aortic syndromes. Identifying these risk factors will refine surveillance strategies and potentially guide preventive interventions for aortic aneurysm.
Article number four. Percutaneous intramyocardial septal radiofrequency ablation: a novel treatment for drug-refractory non-obstructive hypertrophic cardiomyopathy with severe septal hypertrophy. This single-arm, open-label study evaluated the safety and effectiveness of percutaneous intramyocardial septal radiofrequency ablation for drug-refractory non-obstructive hypertrophic cardiomyopathy patients with severe septal hypertrophy. Twenty patients underwent the procedure, with follow-up assessments to determine the impact on symptoms and cardiac function. Percutaneous intramyocardial septal radiofrequency ablation offers a new invasive treatment option for this challenging patient population.
Article number five. Relationship Between Electrical and Morphological Alterations of the Right Ventricle in Arrhythmogenic Right Ventricular Cardiomyopathy. This retrospective study investigated the spatial relationship between low-voltage areas detected during electrophysiological mapping and morphofunctional abnormalities seen on computed tomography imaging in patients with arrhythmogenic right ventricular cardiomyopathy. The right ventricle was divided into seven regions, and the correlation between electrical and structural changes was analyzed. Understanding this relationship may improve the targeting of ventricular tachycardia ablation and risk stratification in arrhythmogenic right ventricular cardiomyopathy.
Thank you for listening. Don’t forget to subscribe.
Keywords
computed tomography, right ventricle, premature menopause, vascular endothelial growth factor inhibitors, hypertension, surveillance, Liwen procedure, cancer therapy-related cardiac dysfunction, cardiometabolic disease, non-obstructive hypertrophic cardiomyopathy, septal hypertrophy, risk factors, genetic risk, thoracic aortic aneurysm, radiofrequency ablation, female-specific factors, cardiovascular magnetic resonance imaging, ventricular tachycardia ablation, arrhythmogenic right ventricular cardiomyopathy, aortic progression, low-voltage areas, adverse pregnancy outcomes, cardiotoxicity, percutaneous intramyocardial septal radiofrequency ablation, ascending aortic dilation.
About
Concise summaries of cardiovascular research for professionals.
Subscribe • Share • FollowThe post Aortic Dilation: New Predictors of Rapid Progression 09/14/25 first appeared on Cardiology Today.
Article Links:
Article 1: Vascular endothelial growth factor inhibitor-induced cardiotoxicity: prospective multimodality assessment incorporating cardiovascular magnetic resonance imaging. (Heart (British Cardiac Society))
Article 2: Synergistic effects of female-specific conditions and genetic risk on cardiometabolic disease: a cohort study. (Heart (British Cardiac Society))
Article 3: Follow-up of incidentally detected mild to moderate ascending aortic dilation and risk factors for rapid progression in a Swedish middle-aged population. (Heart (British Cardiac Society))
Article 4: Percutaneous intramyocardial septal radiofrequency ablation: a novel treatment for drug-refractory non-obstructive hypertrophic cardiomyopathy with severe septal hypertrophy. (Heart (British Cardiac Society))
Article 5: Relationship Between Electrical and Morphological Alterations of the Right Ventricle in Arrhythmogenic Right Ventricular Cardiomyopathy. (Heart rhythm)
Full episode page: https://podcast.explainheart.com/podcast/aortic-dilation-new-predictors-of-rapid-progression-09-14-25/
Featured Articles
Article 1: Vascular endothelial growth factor inhibitor-induced cardiotoxicity: prospective multimodality assessment incorporating cardiovascular magnetic resonance imaging.
Journal: Heart (British Cardiac Society)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40180444
Summary: This study prospectively evaluated cardiotoxicity in patients receiving vascular endothelial growth factor inhibitors for cancer treatment, utilizing blood pressure monitoring, echocardiography, and cardiac biomarkers. The research aims to define the incidence, time course, and mechanisms of vascular endothelial growth factor inhibitor associated cancer therapy-related cardiac dysfunction and hypertension through a multi-modal approach including cardiovascular magnetic resonance imaging. The study is ongoing and will provide insights into early detection and management of cardiotoxicity in this patient population.
Article 2: Synergistic effects of female-specific conditions and genetic risk on cardiometabolic disease: a cohort study.
Journal: Heart (British Cardiac Society)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40139682
Summary: This prospective cohort study of over 150,000 women from the United Kingdom Biobank examined the association between female-specific factors like premature menopause, adverse pregnancy outcomes, and early or late menarche, and the occurrence and progression of cardiometabolic disease. The study aims to determine how these factors interact with genetic risk to influence cardiometabolic health in women. Understanding these interactions will help refine risk stratification and prevention strategies for cardiometabolic disease in women.
Article 3: Follow-up of incidentally detected mild to moderate ascending aortic dilation and risk factors for rapid progression in a Swedish middle-aged population.
Journal: Heart (British Cardiac Society)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40081936
Summary: This study investigated the progression of incidentally detected mild to moderate ascending aortic dilation in a Swedish population aged 50-65 years. Researchers followed over 5,000 participants to identify risk factors associated with rapid aortic dilation, which can lead to life-threatening aortic syndromes. Identifying these risk factors will refine surveillance strategies and potentially guide preventive interventions for aortic aneurysm.
Article 4: Percutaneous intramyocardial septal radiofrequency ablation: a novel treatment for drug-refractory non-obstructive hypertrophic cardiomyopathy with severe septal hypertrophy.
Journal: Heart (British Cardiac Society)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40054888
Summary: This single-arm, open-label study evaluated the safety and effectiveness of percutaneous intramyocardial septal radiofrequency ablation for drug-refractory non-obstructive hypertrophic cardiomyopathy patients with severe septal hypertrophy. Twenty patients underwent the procedure, with follow-up assessments to determine the impact on symptoms and cardiac function. Percutaneous intramyocardial septal radiofrequency ablation offers a new invasive treatment option for this challenging patient population.
Article 5: Relationship Between Electrical and Morphological Alterations of the Right Ventricle in Arrhythmogenic Right Ventricular Cardiomyopathy.
Journal: Heart rhythm
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40945559
Summary: This retrospective study investigated the spatial relationship between low-voltage areas detected during electrophysiological mapping and morphofunctional abnormalities seen on computed tomography imaging in patients with arrhythmogenic right ventricular cardiomyopathy. The right ventricle was divided into seven regions, and the correlation between electrical and structural changes was analyzed. Understanding this relationship may improve the targeting of ventricular tachycardia ablation and risk stratification in arrhythmogenic right ventricular cardiomyopathy.
Transcript
Today’s date is September 14, 2025. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Vascular endothelial growth factor inhibitor-induced cardiotoxicity: prospective multimodality assessment incorporating cardiovascular magnetic resonance imaging. This study prospectively evaluated cardiotoxicity in patients receiving vascular endothelial growth factor inhibitors for cancer treatment, utilizing blood pressure monitoring, echocardiography, and cardiac biomarkers. The research aims to define the incidence, time course, and mechanisms of vascular endothelial growth factor inhibitor associated cancer therapy-related cardiac dysfunction and hypertension through a multi-modal approach including cardiovascular magnetic resonance imaging. The study is ongoing and will provide insights into early detection and management of cardiotoxicity in this patient population.
Article number two. Synergistic effects of female-specific conditions and genetic risk on cardiometabolic disease: a cohort study. This prospective cohort study of over 150,000 women from the United Kingdom Biobank examined the association between female-specific factors like premature menopause, adverse pregnancy outcomes, and early or late menarche, and the occurrence and progression of cardiometabolic disease. The study aims to determine how these factors interact with genetic risk to influence cardiometabolic health in women. Understanding these interactions will help refine risk stratification and prevention strategies for cardiometabolic disease in women.
Article number three. Follow-up of incidentally detected mild to moderate ascending aortic dilation and risk factors for rapid progression in a Swedish middle-aged population. This study investigated the progression of incidentally detected mild to moderate ascending aortic dilation in a Swedish population aged 50-65 years. Researchers followed over 5,000 participants to identify risk factors associated with rapid aortic dilation, which can lead to life-threatening aortic syndromes. Identifying these risk factors will refine surveillance strategies and potentially guide preventive interventions for aortic aneurysm.
Article number four. Percutaneous intramyocardial septal radiofrequency ablation: a novel treatment for drug-refractory non-obstructive hypertrophic cardiomyopathy with severe septal hypertrophy. This single-arm, open-label study evaluated the safety and effectiveness of percutaneous intramyocardial septal radiofrequency ablation for drug-refractory non-obstructive hypertrophic cardiomyopathy patients with severe septal hypertrophy. Twenty patients underwent the procedure, with follow-up assessments to determine the impact on symptoms and cardiac function. Percutaneous intramyocardial septal radiofrequency ablation offers a new invasive treatment option for this challenging patient population.
Article number five. Relationship Between Electrical and Morphological Alterations of the Right Ventricle in Arrhythmogenic Right Ventricular Cardiomyopathy. This retrospective study investigated the spatial relationship between low-voltage areas detected during electrophysiological mapping and morphofunctional abnormalities seen on computed tomography imaging in patients with arrhythmogenic right ventricular cardiomyopathy. The right ventricle was divided into seven regions, and the correlation between electrical and structural changes was analyzed. Understanding this relationship may improve the targeting of ventricular tachycardia ablation and risk stratification in arrhythmogenic right ventricular cardiomyopathy.
Thank you for listening. Don’t forget to subscribe.
Keywords
computed tomography, right ventricle, premature menopause, vascular endothelial growth factor inhibitors, hypertension, surveillance, Liwen procedure, cancer therapy-related cardiac dysfunction, cardiometabolic disease, non-obstructive hypertrophic cardiomyopathy, septal hypertrophy, risk factors, genetic risk, thoracic aortic aneurysm, radiofrequency ablation, female-specific factors, cardiovascular magnetic resonance imaging, ventricular tachycardia ablation, arrhythmogenic right ventricular cardiomyopathy, aortic progression, low-voltage areas, adverse pregnancy outcomes, cardiotoxicity, percutaneous intramyocardial septal radiofrequency ablation, ascending aortic dilation.
About
Concise summaries of cardiovascular research for professionals.
Subscribe • Share • FollowThe post Aortic Dilation: New Predictors of Rapid Progression 09/14/25 first appeared on Cardiology Today.
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